Monday, 13 January 2014

A Glimmer of Hope Foundation

A Glimmer of Hope Foundation was established by Texas-based philanthropists Philip Berber and Donna Berber to lessen severe poverty in rural Ethiopia. In 2010, Philip and Donna were graded #7 by Barron's in its list of '25 Best Givers' in the world, and dubbed as "capitalist crusaders," by the New York Times Magazine. 

From 2001 to 2010, the foundation had sponsored over 4,000 projects all through the country. A Glimmer of Hope also runs a local program within Austin for at-risk youth and senior citizens.

A Glimmer of Hope was set up by the Berbers in the year 2000 using $100 million in proceeds from the sale of online trading company CyBerCorp to Charles Schwab. The base employs a business-based model, with the aim of being an independent charity. 

The foundation is headquartered in Austin, Texas, and runs a national office in Addis Ababa, Ethiopia.

Thursday, 28 February 2013

The A Glimmer of Hope Foundation

The A Glimmer of Hope Foundation was founded by Texas-based philanthropists Philip Berber and Donna Berber to reduce extreme poverty in rural Ethiopia. In 2010, Philip and Donna were ranked #7 by Barron's in its list of '25 Best Givers' in the world, and dubbed as "capitalist crusaders," by the New York Times Magazine. From 2001 to 2010, the foundation had funded more than 4,000 projects throughout the country. A Glimmer of Hope also runs a local program within Austin for at-risk youth and senior citizens.

A Glimmer of Hope was founded by the Berbers in the year 2000 using $100 million in proceeds from the sale of online trading company CyBerCorp to Charles Schwab. The foundation uses a business-based model, with the goal of being a self-sustaining charity. The foundation is headquartered in Austin, Texas, and runs a national office in Addis Ababa, Ethiopia.

Tuesday, 17 July 2012

A Glimmer of Hope Foundation

The A Glimmer of Hope Foundation was founded by Texas-based philanthropists Philip Berber and Donna Berber to reduce extreme poverty in rural Ethiopia. In 2010, Philip and Donna were ranked #7 by Barron's in its list of '25 Best Givers' in the world,[1] and dubbed as "capitalist crusaders," by the New York Times Magazine. From 2001 to 2010, the foundation had funded more than 4,000 projects throughout the country.A Glimmer of Hope also runs a local program within Austin for at-risk youth and senior citizens.

Monday, 5 September 2011

GLIMMER

GLIMMER (Gene Locator and Interpolated Markov ModelER) was the first bioinformatics system for finding genes that used the interpolated Markov model formalism. It is very effective at finding genes in bacteria, archaea, and viruses, typically finding 98–99% of all protein-coding genes. The GLIMMER software is open source and can be found at the links below. It is maintained by Steven Salzberg, Art Delcher, and their colleagues at the Center for Bioinformatics and Computational Biology at the University of Maryland, College Park.

Because of its exceptionally high accuracy, Glimmer is the system of choice for genome annotation efforts on a wide range of bacteria, archaeal, and viral species. In a large-scale reannotation effort at the DNA Data Bank of Japan (DDBJ, which mirrors Genbank), Kosuge et al. (Kosuge et al. 2006) examined the gene finding methods used for 183 genomes. They report that of these projects, Glimmer was the gene finder for 49%, followed by Genemark with 12%, with other algorithms used in 3% or fewer of the projects. (They also reported that 33% of genomes used “other” programs, which in many cases meant that they could not identify the method. Excluding those cases, Glimmer was used for 73% of the genomes for which the methods could be unambiguously identified.) Glimmer was used by the DNA Databank of Japan (DDBJ) to re-annotate all bacterial genomes in the International Nucleotide Sequence Databases (Sugawara et al. 2007). It is also being used by this group to annotate viruses (Hirahata et al. 2007). Glimmer is part of the bacterial annotation pipeline at the National Center for Biotechnology Information (NCB))

(http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html), which also maintains a web server for Glimmer (http://www.ncbi.nlm.nih.gov/genomes/microbes/glimmer_3.cgi), as do sites in Germany (http://tico.gobics.de/), Canada (http://wishart.biology.ualberta.ca/basys), and elsewhere.
Glimmer is one of the most highly cited bioinformatics systems in the scientific literature. According to Google Scholar, as of early 2011 the original (Salzberg et al., 1998) Glimmer article has been cited 581 times and the Glimmer 2.0 article (Delcher et al., 1999) has been cited 950 times.